Childhood haemorrhagic stroke: a 7-year single-centre experience. Issue 12 (20th June 2019)

• Record Type: Journal Article
• Authors: Gerstl, Lucia; Badura, Katharina; Heinen, Florian; Weinberger, Raphael; Peraud, Aurelia; Dorn, Franziska; Bonfert, Michaela V; Berweck, Steffen; O'Callaghan, Finbar J
• Is Part Of: Archives of disease in childhood. Volume 104:Issue 12(2019)
• Page Start: 1198
• Page End: 1202
• Publication Date: 2019-06-20
• Subjects: intracranial bleeding -- paediatric -- haemorrhagic stroke; Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/archdischild-2018-316749
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Background: In recent years, there has been increasing research interest in improving diagnostic and management protocols in childhood arterial ischaemic stroke (AIS). However, childhood stroke comprises, in approximately equal parts, both arterial ischaemic and haemorrhagic stroke (HS). Objective: The aim of this study was to focus on the aetiology, clinical presentation, treatment and short-term outcome of children with spontaneous intracranial bleeding in a university hospital and elucidate differences to childhood AIS. Design: We performed a retrospective analysis of electronic medical records of children (28 days–18 years) diagnosed with HS between 2010 and 2016. Results: We included 25 children (male child, n=11) with a median age of 8 years 1 month. The most common clinical presentations were vomiting (48%), headache (40%) and altered level of consciousness (32%). In more than half of the patients, HS was caused by vascular malformations. Other risk factors were brain tumour, coagulopathy and miscellaneous severe underlying diseases. Aetiology remained unclear in one child. Therapy was neurosurgical in most children (68%). Two patients died, 5 patients needed further (rehabilitation) treatment and 18 children could be discharged home. Conclusions: HS differs from AIS in aetiology (vascular malformations as number one risk factor), number of risk factors ('mono-risk' disease), clinical presentation (vomiting, headache and altered level of consciousness) and (emergency) therapy.