Determination of Three-Dimensional Left Ventricle Motion to Analyze Ventricular Dyssyncrony in SPECT Images. (9th November 2009)

• Record Type: Journal Article
• Authors: Rebelo Rebelo, Marina de Sá Marina de Sá; Aarre Aarre, Ann Kirstine Hummelgaard Ann Kirstine Hummelgaard; Clemmesen Clemmesen, Karen-Louise Karen-Louise; Brandão Brandão, Simone Cristina Soares Simone Cristina Soares; Giorgi Giorgi, Maria Clementina Maria Clementina; Meneghetti Meneghetti, José Cláudio José Cláudio; Gutierrez Gutierrez, Marco Antonio Marco Antonio
• Other Names: Tavares Tavares João Manuel R. S. João Manuel R. S. Academic Editor.
• Is Part Of: EURASIP journal on advances in signal processing. Volume 2010(2010)
• Publication Date: 2009-11-09
• Subjects: Signal processing -- Periodicals; Traitement du signal; Signal processing; Periodicals; 621.3822
• DOI: 10.1155/2010/290695
• Languages: English
• ISSNs: 1687-6172

Abstract

Abstract : A method to compute three-dimension (3D) left ventricle (LV) motion and its color coded visualization scheme for the qualitative analysis in SPECT images is proposed. It is used to investigate some aspects of Cardiac Resynchronization Therapy (CRT). The method was applied to 3D gated-SPECT images sets from normal subjects and patients with severe Idiopathic Heart Failure, before and after CRT. Color coded visualization maps representing the LV regional motion showed significant difference between patients and normal subjects. Moreover, they indicated a difference between the two groups. Numerical results of regional mean values representing the intensity and direction of movement in radial direction are presented. A difference of one order of magnitude in the intensity of the movement on patients in relation to the normal subjects was observed. Quantitative and qualitative parameters gave good indications of potential application of the technique to diagnosis and follow up of patients submitted to CRT.