A biaryl-cyclohexenone photoelectrocyclization/dearomatization sequence to substituted terpenes. (26th January 2023)

• Record Type: Journal Article
• Authors: Satyanarayana Tummalapalli, K.S.; Zhao, Xuchen; Rainier, Jon D.
• Is Part Of: Tetrahedron. Volume 131(2023)
• Publication Date: 2023-01-26
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2022.133180
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: Described here is the development of sequential cross-coupling, photoelectrocyclizations, and reductive dearomatizations of biaryl cyclohexenones as a means of synthesizing terpene skeletons. This methodology promises to provide insight that will enable us and others to use this approach to generate a variety of biologically active small molecules, including members of the abietane and morphinan skeletons. Graphical abstract: Image 1