Construction and Study of the Application of Novel Norfloxacin Fluorescent Probes. Issue 1 (March 2021)

• Record Type: Journal Article
• Authors: Lv, Kuilin; Wan, Detian; Wang, Lei; Lv, Yuguang
• Is Part Of: IOP conference series. Volume 706:Issue 1(2021)
• Publication Date: 2021-03
• Subjects: Norfloxacin -- Cyano-cyanohydrin -- Fluorescence probe -- Charge transfer; Earth sciences -- Periodicals; Environmental sciences -- Congresses; Environmental sciences -- Periodicals; 550.5
• DOI: 10.1088/1755-1315/706/1/012034
• Languages: English
• ISSNs: 1755-1307

Abstract

Abstract: In this experiment, a fluorescent probe of tricyanohydrofuran-norfloxacin was successfully constructed. Fluorescence spectrophotometer was used to detect the fluorescence intensity of the system under the condition of the excitation wavelength was 362nm and the emission wavelength was 448nm. The optimal experimental conditions were optimized (the concentration of the complex, the amount of norfloxacin, pH, temperature and reaction time). The optimal concentration of the complex in the system is in the range of 1.0×10 −3 -3.5×10 −4 mol·L −1, the dosage was 0.6mL, and optimal dosage of norfloxacin was 3.0 ml, the optimum pH of the system was 5.5, under this condition the fluorescence intensity of the system was the strongest. At the same time, the intramolecular charge transfer reaction mechanism of fluorescent probe was studied. And testing the content of norfloxacin capsules, the results were satisfactory. A new testing method of norfloxacin content successfully created.