Morphology study of SPIONs coated apoferritin using small-angle neutron/X-ray scattering and transmission electron microscopy. (January 2020)

• Record Type: Journal Article
• Authors: Patriati, A; Lubis, W Z; Suparno, N; Soontaranoon, S; Mujamilah,
• Is Part Of: Journal of physics. Volume 1436(2020)
• Publication Date: 2020-01
• Subjects: Physics -- Congresses; 530.5
• DOI: 10.1088/1742-6596/1436/1/012111
• Languages: English
• ISSNs: 1742-6588

Abstract

Abstract: The morphology structure of super paramagnetic iron nanoparticle (Fe3 O4 / γ -Fe2 O3 ) or SPIONs coated by apoferritin was studied to understand the ability of apoferritin in coating iron oxide. The system was synthesized in a solution to approach the human body's physiological condition. Small-angle neutron and x-ray scattering (SANS and SAXS) techniques were conducted to reveal the nanostructure of the nanoparticle. The fractal structure was observed by SANS for the SPIONs itself, with the diameter of the building sphere was 2.8 nm. Meanwhile, the SAXS data suited a model of the polydisperse sphere, which assumed as the existence of coated and non-coated SPIONs apoferritin and free apoferritin itself. Transmission Electron Microscopy (TEM) data confirmed the assumption and concluded that apoferritin unable to cover all the iron oxide.