Influence of Sexual Hormones on Neural Orofacial Perception. Issue 8 (15th December 2016)
- Record Type:
- Journal Article
- Title:
- Influence of Sexual Hormones on Neural Orofacial Perception. Issue 8 (15th December 2016)
- Main Title:
- Influence of Sexual Hormones on Neural Orofacial Perception
- Authors:
- Alves, Bruna
Ibuki, Flavia
Gonçalves, Alyne Simões
Teixeira, Manoel Jacobsen
De Siqueira, Silvia Regina Dowgan Tesseroli - Abstract:
- Abstract: Objective. To investigate the trigeminal somatosensory (thermal, pain, tactile, vibratory, and electric), gustative (salty, bitter, sweet, sour), and olfactory thresholds in healthy women during the menstrual cycle and investigate any association with estradiol and progesterone levels in saliva. Methods. We examined/tested 39 women between age 19 and 47 years and with regular menstrual cycles and no comorbidities. All women were informed about the purposes of the study, and only those who signed the informed consent were included. The tests were performed at three stages within the cycle: menstrual phase, follicular phase, and luteal phase. The procedure consisted of saliva collection at the beginning of each session to measure hormone levels, salivary flow, somatosensory evaluation with quantitative sensory testing applied to the right trigeminal maxillary branch and right forearm, gustative (sweet [glucose], salt [sodium chloride], sour [citric acid], and bitter [urea]) and olfactory (isopropanol at different concentrations) thresholds. Results. During the menstrual cycle, thresholds for sweet, salty, sour, cold, vibration, and deep pain decreased, but warmth, electrical, and superficial pain thresholds increased. The bitter threshold was high, and the olfactory threshold was low in the follicular phase. Low estrogen levels were correlated to high deep pain thresholds in the forearm ( P = 0.008) and face ( P = 0.041), high tactile thresholds ( P = 0.001),Abstract: Objective. To investigate the trigeminal somatosensory (thermal, pain, tactile, vibratory, and electric), gustative (salty, bitter, sweet, sour), and olfactory thresholds in healthy women during the menstrual cycle and investigate any association with estradiol and progesterone levels in saliva. Methods. We examined/tested 39 women between age 19 and 47 years and with regular menstrual cycles and no comorbidities. All women were informed about the purposes of the study, and only those who signed the informed consent were included. The tests were performed at three stages within the cycle: menstrual phase, follicular phase, and luteal phase. The procedure consisted of saliva collection at the beginning of each session to measure hormone levels, salivary flow, somatosensory evaluation with quantitative sensory testing applied to the right trigeminal maxillary branch and right forearm, gustative (sweet [glucose], salt [sodium chloride], sour [citric acid], and bitter [urea]) and olfactory (isopropanol at different concentrations) thresholds. Results. During the menstrual cycle, thresholds for sweet, salty, sour, cold, vibration, and deep pain decreased, but warmth, electrical, and superficial pain thresholds increased. The bitter threshold was high, and the olfactory threshold was low in the follicular phase. Low estrogen levels were correlated to high deep pain thresholds in the forearm ( P = 0.008) and face ( P = 0.041), high tactile thresholds ( P = 0.001), and high superficial pain ( P = 0.006) thresholds in the face. High levels of progesterone were associated with a high deep pain threshold in the face and a high salty threshold ( P < 0.001). Conclusion. Estrogen and progesterone seem to be involved in sensory neuromodulation in women during the menstrual cycle. … (more)
- Is Part Of:
- Pain medicine. Volume 18:Issue 8(2017)
- Journal:
- Pain medicine
- Issue:
- Volume 18:Issue 8(2017)
- Issue Display:
- Volume 18, Issue 8 (2017)
- Year:
- 2017
- Volume:
- 18
- Issue:
- 8
- Issue Sort Value:
- 2017-0018-0008-0000
- Page Start:
- 1549
- Page End:
- 1556
- Publication Date:
- 2016-12-15
- Subjects:
- Sensitivity -- Somatosensory Perception -- Menstrual Cycle -- Quantitative Sensory Testing -- Estrogen and Progesterone
Pain -- Periodicals
Pain -- Treatment -- Periodicals
Analgesics -- Periodicals
Pain -- Periodicals
Pain Management -- Periodicals
Douleur -- Périodiques
Douleur -- Traitement -- Périodiques
Analgésiques -- Périodiques
Analgésique
Soulagement de la douleur
Périodique électronique (Descripteur de forme)
Ressource Internet (Descripteur de forme)
616.047205 - Journal URLs:
- http://firstsearch.oclc.org ↗
http://firstsearch.oclc.org/journal=1526-2375;screen=info;ECOIP ↗
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1526-4637 ↗
http://www.blackwell-synergy.com/member/institutions/issuelist.asp?journal=pme ↗
http://painmedicine.oxfordjournals.org/ ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1093/pm/pnw272 ↗
- Languages:
- English
- ISSNs:
- 1526-2375
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6333.806000
British Library DSC - BLDSS-3PM
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- 25188.xml