Neutral Theory Is the Foundation of Conservation Genetics. (16th April 2018)

• Record Type: Journal Article
• Authors: Yoder, Anne D; Poelstra, Jelmer W; Tiley, George P; Williams, Rachel C
• Editors: Kumar, Sudhir
• Is Part Of: Molecular biology and evolution. Volume 35:Number 6(2018)
• Page Start: 1322
• Page End: 1326
• Publication Date: 2018-04-16
• Subjects: demography -- cryptic species -- coalescent methods -- biodiversity -- effective population size -- genomics; Molecular biology -- Periodicals; Molecular evolution -- Periodicals; Evolution, Molecular -- Periodicals; Molecular Biology -- Periodicals; 572.8
• DOI: 10.1093/molbev/msy076
• Languages: English
• ISSNs: 0737-4038

Abstract

Abstract: Kimura's neutral theory of molecular evolution has been essential to virtually every advance in evolutionary genetics, and by extension, is foundational to the field of conservation genetics. Conservation genetics utilizes the key concepts of neutral theory to identify species and populations at risk of losing evolutionary potential by detecting patterns of inbreeding depression and low effective population size. In turn, this information can inform the management of organisms and their habitat providing hope for the long-term preservation of both. We expand upon Avise's "inventorial" and "functional" categories of conservation genetics by proposing a third category that is linked to the coalescent and that we refer to as "process-driven." It is here that connections between Kimura's theory and conservation genetics are strongest. Process-driven conservation genetics can be especially applied to large genomic data sets to identify patterns of historical risk, such as population bottlenecks, and accordingly, yield informed intuitions for future outcomes. By examining inventorial, functional, and process-driven conservation genetics in sequence, we assess the progression from theory, to data collection and analysis, and ultimately, to the production of hypotheses that can inform conservation policies.