Gastric dilatation in patients with restrictive eating disorders. Issue 12 (26th October 2022)

• Record Type: Journal Article
• Authors: Gibson, Dennis; Watters, Ashlie; Dee, Elizabeth; Mehler, Philip S.
• Is Part Of: International journal of eating disorders. Volume 55:Issue 12(2022)
• Page Start: 1853
• Page End: 1858
• Publication Date: 2022-10-26
• Subjects: anorexia nervosa -- avoidant/restrictive food intake disorder -- eating disorders -- gastric dilatation -- gastric dimension -- malnutrition; Appetite disorders -- Periodicals; Ingestion disorders -- Periodicals; Eating disorders -- Periodicals; 616.8526
• DOI: 10.1002/eat.23839
• Languages: English
• ISSNs: 0276-3478

Abstract

Abstract: Objectives: To better understand gastric dimensions in patients diagnosed with restrictive eating disorders (EDs). Method: In this retrospective study, 56 patients, with restrictive EDs, and 60 gender/age/race‐matched patients from an outpatient clinic, were studied. Difference in stomach size, between cohorts, was ascertained, and regression analyses were used to examine associations with stomach size in the ED cohort. Results: Patients with EDs were found to have significantly enlarged gastric dimensions when compared to the control group (M:14.8 cm [SD: 3.2] vs. 11.4 cm [SD: 2.9], p < .0001). Among the ED cohort, blood urea nitrogen (BUN), on the day of imaging, positively correlated with gastric dimensions ( r = .43, p = .0009), while hypoalbuminemia negatively correlated with gastric dimensions ( r = −.37, p = .005). BUN and albumin nadir were also significantly associated with stomach size ( r 2 = .26, F [2, 53] = 9.46, p = .0003). There was no significant correlation between gastric dimensions and ED diagnosis, percent ideal body weight, gender, duration of illness, engagement in vomiting behaviors, diagnosis of superior mesenteric artery syndrome, or use of promotility agents. Discussion: Findings in this study suggest that malnutrition, secondary to EDs, may be associated with an enlarged stomach. The relationship between the gastric dimensions and reported GI symptoms in this population remain to be determined. Public significance: There are many physiologic changes to the gastrointestinal system that develop with malnutrition but the contribution of these physiologic changes toward the reported GI symptoms and refeeding difficulties is unclear. This is the first study to suggest that patients with malnutrition, secondary to EDs, may be associated with an enlarged stomach, and this potential relationship requires further investigation.