Chloride Binding Modulated by Anion Receptors Bearing Tetrazine and Urea. Issue 2 (20th October 2022)

• Record Type: Journal Article
• Authors: Plais, Romain; Gouarin, Guy; Bournier, Amélie; Zayene, Olfa; Mussard, Vanessa; Bourdreux, Flavien; Marrot, Jérome; Brosseau, Arnaud; Gaucher, Anne; Clavier, Gilles; Salpin, Jean‐Yves; Prim, Damien
• Is Part Of: Chemphyschem. Volume 24:Issue 2(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-10-20
• Subjects: anion-π interaction -- fluorescence -- hydrogen bonding -- anion receptor; Chemistry, Physical and theoretical -- Periodicals; 541.05
• DOI: 10.1002/cphc.202200524
• Languages: English
• ISSNs: 1439-4235

Abstract

Abstract: Modulation and fine‐tuning of the strength of weak interactions to bind anions are described in a series of synthetic receptors. The general design of the receptors includes both a urea motif and a tetrazine motif. The synthetic sequence towards three receptors is detailed. Impacts of H‐bond strength and linker length between urea and tetrazine on chloride complexation are studied. Binding properties of the chloride anion are examined in both the ground and excited states using a panel of analytical methods (NMR spectroscopy, mass spectrometry, UV/Visible spectroscopies, and fluorescence). A ranking of the receptors by complexation strength has been determined, allowing a better understanding of the structure‐properties relationship on these compounds. Abstract : Structural modifications of a simple anion receptor bearing urea and tetrazine fragments were studied in both ground and excited states. Receptor 2 shows slightly improved chloride complexation compared to the published receptor 4 .