One‐step synthesis of silver nanostructures using Heracleum persicum fruit extract, their cytotoxic activity, anti‐cancer and anti‐oxidant activities. (27th November 2022)

• Record Type: Journal Article
• Authors: Dehnoee, Ali; Javad Kalbasi, Roozbeh; Zangeneh, Mohammad Mahdi; Delnavazi, Mohammad‐Reza; Zangeneh, Akram
• Is Part Of: Micro & nano letters. Volume 18:Number 1(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-11-27
• Subjects: breast adenocarcinoma -- cell viability -- green nanoparticles -- plant extract -- silver nanostructures; Nanotechnology -- Periodicals; Nanostructures -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1049/mna2.12153
• Languages: English
• ISSNs: 1750-0443

Abstract

Abstract: Bio‐inspired techniques are used for synthesis in terms of application, green chemical research, facile, and eco‐friendly chemistry study of silver nanostructures utilizing plant extracts as natural reducing/stabilization and solid adjuvants without the use of toxic and damaging reagents. The present study investigates the biosynthesis of Ag nanoparticles via the mediation of the methanolic extract of Heracleum persicum seeds, without utilizing any stabilizer or surfactant. These nanostructures were identified utilizing ultraviolet–visible spectroscopy, field emission scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, X‐ray diffraction, high‐resolution transmission electron microscopy, Fourier‐transform infrared spectroscopy and dynamic light scattering. The attributes of AgNPs versus usual human breast adenocarcinoma cell lines that is, Hs 281.T, MDA‐MB‐468, AU565 [AU‐565], MCF7, CAMA‐1, SK‐BR‐3, NMU, and RBA were evaluated. The livability of breast adenocarcinoma cell line diminishes dose‐dependently in the existence of AgNPs. After clinical studies, AgNPs can be used as a green drug in the treatment of human breast adenocarcinoma. Abstract : The biosynthesis of Ag nanoparticles via the mediation of the methanolic extract of Heracleum persicum seeds, without utilizing any stabilizer or surfactant, is described. The AgNPs was assessed in biological applications like cytotoxicity and anticancer activities against common human breast adenocarcinoma cell lines.