Innentitelbild: Parahydrogen‐Induced Carbon‐13 Radiofrequency Amplification by Stimulated Emission of Radiation (Angew. Chem. 5/2023). (28th December 2022)

• Record Type: Journal Article
• Authors: Nelson, Christopher; Schmidt, Andreas B.; Adelabu, Isaiah; Nantogma, Shiraz; Kiselev, Valerij G.; Abdurraheem, Abubakar; de Maissin, Henri; Lehmkuhl, Sören; Appelt, Stephan; Theis, Thomas; Chekmenev, Eduard Y.
• Is Part Of: Angewandte Chemie. Volume 135:Number 5(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-12-28
• Subjects: Carbon-13 -- Hyperpolarization -- NMR Spectroscopy -- Parahydrogen -- RASER; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.202218484
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract : Carbon‐13 radiofrequency amplification by stimulated emission of radiation (C‐13 RASER) is demonstrated on a bolus of liquid hyperpolarized ethyl [1‐ 13 C]acetate, as reported by Thomas Theis, Eduard Y. Chekmenev et al. in their Communication (e202215678) . Spontaneous RASER signal emissions were detected using a 1.4 T NMR spectrometer equipped with a standard radiofrequency detection coil for over three minutes. RASER detection enables new detection schemes for 13 C‐hyperpolarized contrast agents and particular new opportunities for next‐generation molecular imaging on clinical MRI scanners.