Should we reduce routine surveillance imaging in pediatric germ cell tumors?. Issue 3 (10th January 2023)

• Record Type: Journal Article
• Authors: Terenziani, Monica; Barretta, Francesco; Gattuso, Giovanna; Bisogno, Gianni; Conte, Massimo; Crocoli, Alessandro; De Pasquale, Maria Debora; Biasoni, Davide; Spreafico, Filippo; D'Angelo, Paolo
• Is Part Of: Pediatric blood & cancer. Volume 70:Issue 3(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-01-10
• Subjects: germ cell tumors -- radiological exposure -- serum tumor markers -- surveillance; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Cancer in children -- Periodicals; 618.92
• DOI: 10.1002/pbc.30200
• Languages: English
• ISSNs: 1545-5009

Abstract

Abstract: This paper retrospectively investigated the site and the detection method of relapses in children and adolescents with malignant germ cell tumors enrolled in the TCGM‐AIEOP‐2004 Study and subsequently developed a relapse, in order to evaluate a possible reduction in radiological exposure during follow‐up. Including all malignant cases, serum tumor markers identified a relapse in more than 70% and, according to the selection criteria published by Children Oncology Group in 2018, in more than 90% of cases. These results confirm the importance of serum tumor markers as a relapse detection method, with possible reduction of radiology exams in specific subgroups.