Early surgery or conservative management for asymptomatic severe aortic stenosis: Meta‐analysis of RECOVERY and AVATAR. Issue 12 (6th November 2022)

• Record Type: Journal Article
• Authors: Changal, Khalid; Devarasetty, Pratyush Pavan; Royfman, Rachel; Veria, Spiro; Yassen, Mohammad; Vyas, Rohit; Gössl, Mario
• Is Part Of: Journal of cardiac surgery. Volume 37:Issue 12(2022)
• Page Start: 5336
• Page End: 5340
• Publication Date: 2022-11-06
• Subjects: aorta and great vessels -- valve repair/replacement; Heart -- Surgery -- Periodicals; 617.412005
• DOI: 10.1111/jocs.17130
• Languages: English
• ISSNs: 0886-0440

Abstract

Abstract: The standard practice for management for asymptomatic severe aortic stenosis with a normal left ventricular systolic function is conservative management with a few exceptions. This practice is challenged by two recent randomized controlled trials (RCT). All the prior data is observational. We performed a meta‐analysis of these 2 RCTs to determine if early surgical aortic valve replacement in this patient population is beneficial compared with the standard conservative therapy.