Intersectionality of Socioecological Factors Associated With Cognitive Function Among Older Women With HIV in the United States: A Structural Equation Model Analysis Using Data From the Women's Interagency HIV Study. (12th January 2023)

• Record Type: Journal Article
• Authors: Njie-Carr, Veronica P. S.; Zhu, Shijun; Stafford, Kristen A.; Tong, Weiqun; Plankey, Michael; Sharma, Anjali; Milam, Joel; Cohen, Mardge; Diaz, Monica M.; Rubtsova, Anna A.; Fischl, Margaret A.; Konkle-Parker, Deborah; Gustafson, Deborah; Rubin, Leah H.
• Is Part Of: Journal of the Association of Nurses in AIDS Care. Volume 34:Number 1(2023)
• Page Start: 83
• Page End: 95
• Publication Date: 2023-01-12
• Subjects: abuse -- African American -- Black -- cognitive function -- HIV -- mood disorders -- substance use -- women with HIV; AIDS (Disease) -- Nursing -- Periodicals; AIDS (Disease) -- Treatment -- Periodicals; AIDS (Disease) -- Periodicals; HIV infections -- Nursing -- Periodicals; HIV infections -- Treatment -- Periodicals; HIV infections -- Periodicals; 616.97920231
• DOI: 10.1097/JNC.0000000000000376
• Languages: English
• ISSNs: 1055-3290

Abstract

Abstract: Increased life expectancy of people with HIV has health implications including the intersection of the long-term use of antiretroviral treatment, inflammatory events, and age-related immunosenescence. In a cross-sectional study utilizing using the Socio-Eecological Model, we identified pathways of cognitive function (CF) among 448 women with HIV, 50 years and older. A structural equation model showed the direct effects of mood (β = −0.25, p < .01), comorbidities (β = −-0.13, p < .05), race (β = −-0.13, p < .05), and abuse (β = 0.27, p < .001) on the latent variable CF. Substance and alcohol use, depressive symptoms, cigarette smoking, and the number of comorbidities are important considerations when designing interventions utilizing using a multi-level and intersectional lens to maximize positive CF outcomes.