Differences in the risk factors of reflux esophagitis according to age in Korea. Issue 2 (1st March 2014)

• Record Type: Journal Article
• Authors: Park, C. H.; Kim, K. O.; Baek, I. H.; Choi, M. H.; Jang, H. J.; Kae, S. H.; Kim, J. B.; Baik, G. H.; Shin, W. G.; Kim, K. H.; Kim, H. Y.
• Is Part Of: Diseases of the esophagus. Volume 27:Issue 2(2014)
• Page Start: 116
• Page End: 121
• Publication Date: 2014-03-01
• Subjects: gastroesophageal reflux disease -- reflux esophagitis -- risk factor; Esophagus -- Diseases -- Periodicals; 616.32
• DOI: 10.1111/j.1442-2050.2012.01417.x
• Languages: English
• ISSNs: 1120-8694

Abstract

Summary: The prevalence of gastroesophageal reflux disease in K orea has been believed to be low, but the incidence of gastroesophageal reflux disease in Korea is expected to increase because of the longer life expectancy and more ingestion of westernized food. The aim of this study was to report differences in the risk factors of reflux esophagitis (RE ) according to age in K orea. We prospectively recruited the subjects who had RE among those who visited a health promotion center for upper gastrointestinal cancer surveillance at H allym M edical C enter (five institutions) between J anuary 2008 and F ebruary 2009. The enrolled study participants comprised 742 subjects with RE and 1484 healthy controls. The independent risk factors of RE in young and adult group were male sex, smoking, coffee, body mass index ≥ 25, hiatal hernia, and H elicobacter pylori negativity. The risk factors of RE in elderly group were smoking, coffee, and hiatal hernia. The risk factors for RE according to age group were found to differ. In elderly group, H elicobacter pylori infection was not a significant protective factor contrary to young and adult groups.