Pectoralis Major Onlay vs Interpositional Reconstruction Fistulation After Salvage Total Laryngectomy: Systematic Review and Meta‐analysis. (29th September 2020)
- Record Type:
- Journal Article
- Title:
- Pectoralis Major Onlay vs Interpositional Reconstruction Fistulation After Salvage Total Laryngectomy: Systematic Review and Meta‐analysis. (29th September 2020)
- Main Title:
- Pectoralis Major Onlay vs Interpositional Reconstruction Fistulation After Salvage Total Laryngectomy: Systematic Review and Meta‐analysis
- Authors:
- Cabrera, Claudia I.
Joseph Jones, Alexander
Philleo Parker, Noah
Emily Lynn Blevins, Amy
Weidenbecher, Mark S. - Abstract:
- Abstract : Objective: To evaluate the difference in pharygocutaneous fistula (PCF) development between pectoralis major flap onlay and interpositional reconstructions after salvage total laryngectomy (STL). Data Sources: Medline, Cochrane, Embase, Web of Science, CINAHL, and ClinicalTrials.gov. Review Methods: A systematic review was performed during January 2020. English articles were included that described minor and major PCF rates after STL reconstructed with pectoralis major onlay or interposition. PCFs were classified as major when conservative therapy was unsuccessful and/or revision surgery was needed. Articles describing total laryngopharyngectomies were excluded. Meta‐analyses of the resulting data were performed. Results: Twenty‐four articles met final criteria amassing 1304 patients. Three articles compared onlay with interposition, and 18 compared onlay with primary closure. Pectoralis interposition demonstrated elevated odds ratio (OR) of PCF formation as compared with onlay (OR, 2.34; P <. 001). Onlay reconstruction reduced overall (OR, 0.32; P <. 001) and major (OR, 0.21; P <. 001) PCF development as compared with primary pharyngeal closure alone. Data were insufficient to compare interposition against primary closure. Conclusions: This research shows evidence that pectoralis onlay after STL diminishes the odds of total and major PCF development. Pectoralis interposition reconstruction showed elevated odds of PCF formation as compared with pectoralis onlay.
- Is Part Of:
- Otolaryngology--head and neck surgery. Volume 164:Number 5(2021)
- Journal:
- Otolaryngology--head and neck surgery
- Issue:
- Volume 164:Number 5(2021)
- Issue Display:
- Volume 164, Issue 5 (2021)
- Year:
- 2021
- Volume:
- 164
- Issue:
- 5
- Issue Sort Value:
- 2021-0164-0005-0000
- Page Start:
- 972
- Page End:
- 983
- Publication Date:
- 2020-09-29
- Subjects:
- fistula -- laryngectomy -- salvage -- pectoralis major -- pedicled flap -- head and neck cancer
Head -- Surgery -- Periodicals
Neck -- Surgery -- Periodicals
Otolaryngology -- Periodicals
617.51 - Journal URLs:
- http://oto.sagepub.com/content/by/year ↗
http://online.sagepub.com/ ↗
http://www.mosby.com/oto ↗
http://www.sciencedirect.com/science/journal/01945998 ↗ - DOI:
- 10.1177/0194599820957962 ↗
- Languages:
- English
- ISSNs:
- 0194-5998
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6313.523000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 25110.xml