Epidemiology of Uveitis in Olmsted County, Minnesota: A Population-Based Follow-Up Study. (2nd January 2023)

• Record Type: Journal Article
• Authors: Xu, Timothy T.; Reynolds, Margaret M.; Hodge, David O.; Smith, Wendy M.
• Is Part Of: Ocular immunology and inflammation. Volume 31:Number 1(2023)
• Page Start: 112
• Page End: 118
• Publication Date: 2023-01-02
• Subjects: Uveitis -- epidemiology -- population-based; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2021.1988113
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: To update the incidence of uveitis in a Midwestern U.S. county population. Methods: Retrospective population-based cohort study. All Olmsted County, Minnesota residents diagnosed with uveitis from January 1, 2006 to December 31, 2015 were identified via the Rochester Epidemiology Project. Diagnoses were confirmed by a uveitis specialist. Results: There were 371 incident uveitis cases, yielding an overall age- and sex-adjusted incidence rate of 26.9 per 100, 000 per year (95% CI: 24.1–29.7). Females accounted for 202 (54.4%) cases, 306 (82.5%) were White, and 299 (80.6%) were anterior uveitis. Highest incidence was observed in patients ≥65 years old. No difference in incidence existed between sexes ( p = .17). Incidence rates increased with age for uveitis overall (all anatomic subtypes) ( p < .001), anterior uveitis ( p < .001), and posterior uveitis ( p < .001). Idiopathic uveitis accounted for 168 (45.3%) cases, more frequently diagnosed in females (50.0%) than males (39.6%) ( p = .05). Conclusion: Uveitis incidence increased 1.6-fold over a 50-year span in this predominately White U.S. Midwestern county population.