Clinical utility of two-phase computed tomography angiography for the detection of myocardial perfusion defects related to acute coronary syndrome in patients with acute chest pain: a case series. Issue 4 (17th April 2021)

• Record Type: Journal Article
• Authors: Vallejo, Enrique; Buelna-Cano, Christian
• Editors: Arzanauskaite, Monika; Rampat, Rajiv; Gheorghe, Livia; Aimo, Alberto; Mukherjee, Rahul; Guella, Elhosseyn
• Is Part Of: European heart journal. Volume 5:Issue 4(2021)
• Publication Date: 2021-04-17
• Subjects: Acute chest pain -- Acute coronary syndrome -- Myocardial CT perfusion -- Computed tomography angiography -- Emergency department -- Case series; Cardiology -- Periodicals; Cardiology -- Case studies -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Diseases -- Case studies -- Periodicals; 616.12
• DOI: 10.1093/ehjcr/ytab139
• Languages: English
• ISSNs: 2514-2119

Abstract

Abstract: Background: Evaluation of acute chest pain (ACP) in the emergency department is a major health issue and differential diagnosis remains challenging for the physician, particularly in patients with atypical symptoms and inconclusive changes in electrocardiogram (ECG) or biomarkers levels. Case summary: We present the potential value of the two-phase computed tomography angiography (TP-CTA) imaging protocol done in six different patients evaluated with ACP and underwent non-gated or gated computed tomography angiography (CTA) to exclude pulmonary embolism (PE), acute aortic syndrome (AAS), or acute coronary syndrome (ACS). All patients had new-onset chest pain and atypical clinical presentation with non-diagnostic ECG and initially negative or near-normal cardiac biomarkers. Discussion: The evaluation of myocardial computed tomography perfusion (MCTP) using TP-CTA imaging protocol might open a new diagnostic approach to evaluate MCTP in patients with ACP related to PE, AAS, or ACS.