Near‐Infrared Spectroscopic Characterization of Cardiac and Renal Fibrosis in Fixed and Fresh Rat Tissue. Issue 1 (13th December 2022)

• Record Type: Journal Article
• Authors: Adegoke, John A.; Gassner, Callum; Sharma, Varun J.; Patel, Sheila K.; Jackett, Louise; Afara, Isaac O.; Raman, Jaishankar; Burrell, Louise M.; Wood, Bayden R.
• Is Part Of: Analysis & Sensing. Volume 3:Issue 1(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-12-13
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; 543
• DOI: 10.1002/anse.202200106
• Languages: English
• ISSNs: 2629-2742

Abstract

Abstract: Invited for this month's cover are the collaborating group(s) of Center for Biospectroscopy at Monash University and Austin Health at the University of Melbourne, University of Eastern Finland and the University of Queensland. The cover‐art shows a handheld near‐infrared spectroscopic probe to detect fibrosis in real time using a murine model. More information can be found in the Research Article by John A. Adegoke, Jaishankar Raman, Bayden R. Wood, and co‐workers . Abstract : A low‐cost miniaturized near infrared spectrometer in combination with advance data analysis can discriminate between normal and fibrotic tissue in seconds under physiological conditions. The major differences between spectra of healthy and fibrotic tissue were seen in the following absorption bands; 1509, 1581, 1689 and 1725 nm, which can be attributed to disruption to changes in the collagen network. Read more about the story behind the cover in the Cover Profile and about the research itself (DOI: 10.1002/anse.202200030 ).