Nucleophile induced ligand rearrangement reactions of alkoxy- and arylsilanes. Issue 24 (14th June 2019)

• Record Type: Journal Article
• Authors: Docherty, Jamie H.; Dominey, Andrew P.; Thomas, Stephen P.
• Is Part Of: Tetrahedron. Volume 75:Issue 24(2019)
• Page Start: 3330
• Page End: 3335
• Publication Date: 2019-06-14
• Subjects: Catalysis -- Silane -- Reduction -- Redistribution -- Phenylsilane; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2019.04.062
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: The ligand-redistribution reactions of aryl- and alkoxy-hydrosilanes can potentially cause the formation of gaseous hydrosilanes, which are flammable and pyrophoric. The ability of generic nucleophiles to initiate the ligand-redistribution reaction of commonly used hydrosilane reagents was investigated, alongside methods to hinder and halt the formation of hazardous hydrosilanes. Our results show that the ligand-redistribution reaction can be completely inhibited by common electrophiles and first-row transition metal pre-catalysts. Graphical abstract: Image 1