Real-time optimization meets Bayesian optimization and derivative-free optimization: A tale of modifier adaptation. (April 2021)

• Record Type: Journal Article
• Authors: Chanona, E. A. del Rio; Petsagkourakis, P.; Bradford, E.; Graciano, J. E. Alves; Chachuat, B.
• Is Part Of: Computers & chemical engineering. Volume 147(2021)
• Publication Date: 2021-04
• Subjects: Real-time optimization -- Modifier adaptation -- Trust region -- Gaussian process regression -- Bayesian optimization -- Acquisition function -- Model-free RTO; Chemical engineering -- Data processing -- Periodicals; 660.0285
• DOI: 10.1016/j.compchemeng.2021.107249
• Languages: English
• ISSNs: 0098-1354

Abstract

Highlights: Modifier adaptation with embedded GPs to capture plant-model mismatch in cost and constraints. Combination of trust-region ideas and acquisition functions to balance exploration vs exploitation. Enhanced reliability of modifier adaptation with prior (nominal) models compared to model-free RTO. Effectiveness demonstrated on a batch-to-batch photobioreactor optimization with a dozen inputs. Abstract: This paper investigates a new class of modifier-adaptation schemes to overcome plant-model mismatch in real-time optimization of uncertain processes. The main contribution lies in the integration of concepts from the fields of Bayesian optimization and derivative-free optimization. The proposed schemes embed a physical model and rely on trust-region ideas to minimize risk during the exploration, while employing Gaussian process regression to capture the plant-model mismatch in a non-parametric way and drive the exploration by means of acquisition functions. The benefits of using an acquisition function, knowing the process noise level, or specifying a nominal process model are analyzed on numerical case studies, including a semi-batch photobioreactor optimization problem with a dozen decision variables.