A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative. Issue 2 (14th February 2018)
- Record Type:
- Journal Article
- Title:
- A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative. Issue 2 (14th February 2018)
- Main Title:
- A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative
- Authors:
- Zhao, Changkuo
Wang, Xianheng
Yang, Fuhong
Gao, Lei
Wang, Yuhe - Abstract:
- Abstract : A facile synthetic method was developed for a novel acid-sensitive camptothecin norcantharidin acid ester derivative I . The total yield can reach 71%. This method provides several advantages, including high yield and simple working procedure for the synthesis of analogues. The new synthetic compound I has been shown to exhibit better solubility and similar activity against tumour cell lines.
- Is Part Of:
- Royal Society open science. Volume 5:Issue 2(2018)
- Journal:
- Royal Society open science
- Issue:
- Volume 5:Issue 2(2018)
- Issue Display:
- Volume 5, Issue 2 (2018)
- Year:
- 2018
- Volume:
- 5
- Issue:
- 2
- Issue Sort Value:
- 2018-0005-0002-0000
- Page Start:
- Page End:
- Publication Date:
- 2018-02-14
- Subjects:
- camptothecin -- norcantharidin -- synthesis -- water solubility -- tumour
Science -- Periodicals
500 - Journal URLs:
- https://royalsocietypublishing.org/journal/rsos ↗
- DOI:
- 10.1098/rsos.170842 ↗
- Languages:
- English
- ISSNs:
- 2054-5703
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library STI - ELD Digital store
- Ingest File:
- 25060.xml