Rapid Real-time Tracking of Nonpharmaceutical Interventions and Their Association With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Positivity: The Coronavirus Disease 2019 (COVID-19) Pandemic Pulse Study. (2nd September 2020)

• Record Type: Journal Article
• Authors: Clipman, Steven J; Wesolowski, Amy P; Gibson, Dustin G; Agarwal, Smisha; Lambrou, Anastasia S; Kirk, Gregory D; Labrique, Alain B; Mehta, Shruti H; Solomon, Sunil S
• Is Part Of: Clinical infectious diseases. Volume 73:Number 7(2021)
• Page Start: e1822
• Page End: e1829
• Publication Date: 2020-09-02
• Subjects: SARS-CoV-2 -- transmission -- nonpharmaceutical interventions -- social distancing -- testing; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciaa1313
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Background: Current mitigation strategies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rely on the population-wide adoption of nonpharmaceutical interventions (NPIs). Monitoring the adoption of NPIs and their associations with SARS-CoV-2 infection history can provide key information for public health. Methods: We sampled 1030 individuals in Maryland from 17–28 June 2020 to capture sociodemographically and geographically resolved information about NPI adoption and access to SARS-CoV-2 testing, and examine associations with self-reported SARS-CoV-2 positivity. Results: Overall, 92% reported traveling for essential services and 66% visited friends/family. Use of public transport was reported by 18%. In total, 68% reported strict social distancing indoors and 53% reported strict masking indoors; indoor social distancing was significantly associated with age, and race/ethnicity and income were associated with masking. Overall, 55 participants (5.3%) self-reported ever testing positive for SARS-CoV-2, with strong dose-response relationships between several forms of movement frequency and SARS-CoV-2 positivity. In a multivariable analysis, a history of SARS-CoV-2 infection was negatively associated with strict social distancing (adjusted odds ratio [aOR] for outdoor social distancing, 0.10; 95% confidence interval, .03–.33). Only public transport use (aOR for >7 times vs never, 4.3) and visiting a place of worship (aOR for ≥3 times vs never, 16.0) remained significantly associated with SARS-CoV-2 infection after adjusting for strict social distancing and demographics. Conclusions: These results support public health messaging that strict social distancing during most activities can reduce SARS-CoV-2 transmission. Additional considerations are needed for indoor activities with large numbers of persons (places of worship and public transportation), where even NPIs may not be possible or sufficient. Abstract : Strict social distancing was significantly associated with a lower likelihood of severe acute respiratory syndrome coronavirus 2 infection, and attenuated associations between most forms of movement and positivity. Attending worship services and using public transportation remained significantly associated with infection.