Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018. (16th October 2020)

• Record Type: Journal Article
• Authors: Chibwe, Innocent; Kasambara, Watipaso; Kagoli, Mathews; Milala, Harry; Gondwe, Charity; Azman, Andrew S
• Is Part Of: Open forum infectious diseases. Volume 7:Number 11(2020)
• Publication Date: 2020-10-16
• Subjects: cholera -- malawi -- rapid test -- vibrio cholerae; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa493
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 83.0%–98.1%) and a specificity of 95.7% (95% CI, 78.1%–100.0%).