"Chronic Disseminated Aspergillosis, " a Novel Fungal Immune Reconstitution Inflammatory Syndrome. (7th November 2020)

• Record Type: Journal Article
• Authors: Pourbaix, Annabelle; Guery, Romain; Bruneau, Julie; Blanc, Estelle; Jouvion, Gregory; Weinandt, Marthe; Rouzaud, Claire; Lourenço, Jérémy; Boutboul, David; Mira, Jean-Paul; Rouquette, Alexandre; Molina, Thierry Jo; Lecuit, Marc; Lortholary, Olivier
• Is Part Of: Open forum infectious diseases. Volume 7:Number 11(2020)
• Publication Date: 2020-11-07
• Subjects: aspergillosis -- hepatosplenic -- immune reconstitution inflammatory syndrome; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa175
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We report a case of chronic hepatosplenic aspergillosis following immune reconstitution complicating colic aspergillosis in an AIDS patient with multicentric Castleman disease. Symptoms mimicked the clinical presentation of chronic disseminated candidiasis and responded to corticosteroid. This emerging entity enlarges the spectrum of fungal immune reconstitution inflammatory syndrome in the HIV setting.