Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study. (14th October 2020)

• Record Type: Journal Article
• Authors: Ooi, Say Tat; Parthasarathy, Purnima; Lin, Yi; Nallakaruppan, Valliammai D/O; Ng, Shereen; Tan, Teck Choon; Low, Serena; Tang, Terence
• Is Part Of: Open forum infectious diseases. Volume 7:Number 11(2020)
• Publication Date: 2020-10-14
• Subjects: corticosteroids -- COVID-19 -- hydroxychloroquine; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa486
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia. Abstract : Use of corticosteroids and antiviral agent could prevent clinical progression of early COVID-19 pneumonia.