Do I Have HIV or Not? Lack of RNA Detection and the Case for Sensitive DNA Testing. (10th October 2020)

• Record Type: Journal Article
• Authors: Springer, Sandra A; Masciotra, Silvina; Johnson, Jeffrey A; Campbell, Sheldon
• Is Part Of: Open forum infectious diseases. Volume 7:Number 11(2020)
• Publication Date: 2020-10-10
• Subjects: antiretroviral therapy -- diagnostic testing -- DNA -- HIV -- rapid start; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa478
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered in diagnostic guidelines to resolve diagnosis and ensure appropriate ART management.