Bilateral EK Rejection After COVID-19 Vaccine. Issue 11 (November 2021)

• Record Type: Journal Article
• Authors: Abousy, Mya; Bohm, Kelley; Prescott, Christina; Bonsack, Jeanette M.; Rowhani-Farid, Anisa; Eghrari, Allen O.
• Is Part Of: Eye & contact lens. Volume 47:Issue 11(2021)
• Publication Date: 2021-11
• Subjects: Corneal endothelial rejection -- COVID-19 vaccine -- transplant rejection and vaccines; Contact lenses -- Periodicals; Intraocular lenses -- Periodicals; Orthokeratology -- Periodicals; Anterior segment (Eye) -- Diseases -- Periodicals; 617.7523
• DOI: 10.1097/ICL.0000000000000840
• Languages: English
• ISSNs: 1542-2321

Abstract

Abstract : Abstract: Owing to its rapid development, short-term and long-term effects of the COVID-19 vaccine are still not well understood. This case report highlights bilateral corneal endothelial graft rejection after administration of the Pfizer COVID-19 vaccine. A 73-year-old woman with bilateral Descemet stripping endothelial keratoplasty presented with bilateral decreased visual acuity, ocular pain, and photophobia after her second dose of the Pfizer-BioNTech COVID-19 vaccine. Two weeks after vaccine administration, the uncorrected visual acuity was 20/70 and 20/40. Central corneal thickness as measured by ultrasound was 809 and 825 μm and by Scheimfplug imaging was 788 and 751 μm at the pupil center. Slit-lamp biomicroscopy revealed quiet conjunctiva and sclera but was significant for thickened corneas with Descemet folds in both eyes. The patient was instructed to use prednisolone acetate 1% every 1 to 2 hours with Muro ointment at bedtime. Abstract : Supplemental Digital Content is Available in the Text.