Impact of Medication Adherence on Healthcare Resource Utilization, Work Loss, and Associated Costs in a Privately Insured Employed Population Treated With Adalimumab in the United States. Issue 10 (October 2021)

• Record Type: Journal Article
• Authors: Mittal, Manish; Yang, Min; Shah, Manan; Gao, Wei; Carley, Christopher; Sherman, Bruce W.
• Is Part Of: Journal of occupational and environmental medicine. Volume 63:Issue 10(2021)
• Publication Date: 2021-10
• Subjects: adalimumab -- autoimmune disorders -- healthcare costs -- healthcare resource utilization -- medication adherence -- work loss; Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; Occupational Medicine -- Periodicals; Environmental Medicine -- Periodicals; Environmental health; Medicine, Industrial; Periodicals; Electronic journals; 616.9803
• DOI: 10.1097/JOM.0000000000002354
• Languages: English
• ISSNs: 1076-2752

Abstract

Abstract : Objective: The aim of this study was to evaluate the impact of adherence to adalimumab on all-cause work loss, healthcare resource utilization (HRU), and direct medical and indirect costs over 2 years using real-world data. Methods: This was a retrospective cohort study using a large, United States administrative claims database. Adult patients treated with adalimumab were grouped into adherent and non-adherent cohorts and followed for up to 2 years. Outcomes were compared between cohorts. Results: Over 2 years, adherent patients had $10, 214 lower per patient medical and indirect costs compared to non-adherent patients, resulting from lower HRU, fewer days of absenteeism, and lower rates of work loss events. Conclusion: Patient and societal benefits of adherence to adalimumab are significant over 2 years. These findings highlight the importance of policies aimed at improving adherence to self-administrated medications. Abstract : Supplemental Digital Content is available in the text