A novel 1, 8‐naphthalimide‐based fluorescent chemosensor for the detection of HSA in living cells. Issue 1 (19th December 2022)

• Record Type: Journal Article
• Authors: Mo, Liuting; He, Wanqi; Tang, Yonghe; Liang, Danlian; Yang, Chan; Lin, Weiying
• Is Part Of: Luminescence. Volume 38:Issue 1(2023)
• Page Start: 83
• Page End: 88
• Publication Date: 2022-12-19
• Subjects: fluorescent probe -- HSA -- live‐cell imaging -- protein detection; Luminescence -- Periodicals; Bioluminescence -- Periodicals; Chemiluminescence -- Periodicals; Luminescence -- Periodicals; 535.35
• DOI: 10.1002/bio.4421
• Languages: English
• ISSNs: 1522-7235

Abstract

Abstract: Human serum albumin (HSA) is an essential protein for maintaining human health. Accurate detection and quantification of HSA are of great significance for disease diagnosis and biochemical research. Here, a new HSA fluorescent probe BNPE based on the 1, 8‐naphthalimide fluorophore was designed and synthesized. The probe could recognize HSA through a twisted intramolecular charge transfer mechanism, effectively avoid the interference of most substances, and realize HSA fluorescence imaging in living cells.