Is intraoperative corticosteroid a good choice for postoperative pain relief in total joint arthroplasty? A meta-analysis of 11 randomized controlled trials. Issue 40 (8th October 2021)

• Record Type: Journal Article
• Authors: Zhang, Lu-kai; Zhu, Fang-bing; Gao, Huan-huan; Zhang, Lei; Quan, Ren-fu
• Other Names: Li. Yan section editor.
• Is Part Of: Medicine. Volume 100:Issue 40(2021)
• Publication Date: 2021-10-08
• Subjects: analgesia -- corticosteroid -- meta-analysis -- total joint arthroplasty; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000027468
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Background: Effective postoperative analgesia is of great significance for postoperative rehabilitation. This meta-analysis aimed to investigate the efficacy of corticosteroid on pain following total joint arthroplasty. Method: PubMed (1996–December 2020), Embase (1996–December 2020), and the Cochrane Library (CENTRAL, December 2020) were searched and a total of 11 randomized controlled trials met our inclusion criteria. Results: Eleven randomized controlled trials met the inclusion criteria. Pooled data indicated the corticosteroid group was effective compared to the control group in terms of the visual analogue scale at rest ( P < .05) and movement ( P < .05), the total morphine equivalent consumption ( P < .05), and the length of stay ( P < .05), without increasing the risk of periprosthetic joint infection ( P = .74) and the length of stay ( P = .32). Conclusions: Compared to the control group, intraoperative corticosteroid was benefit to the pain management in total joint arthroplasty.