Albumin Use in Brain-injured and Neurosurgical Patients: Concepts, Indications, and Controversies. Issue 4 (October 2021)

• Record Type: Journal Article
• Authors: Ma, Heung Kan; Bebawy, John F.
• Is Part Of: Journal of neurosurgical anesthesiology. Volume 33:Issue 4(2021)
• Publication Date: 2021-10
• Subjects: human serum albumin -- intravenous infusion -- neurosurgery -- neurosurgical anesthesia -- neuroanesthesia -- perioperative care; Anesthesia in neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; 617.96748
• DOI: 10.1097/ANA.0000000000000674
• Languages: English
• ISSNs: 0898-4921

Abstract

Abstract : Human albumin has been used extensively for decades as a nonwhole blood plasma replacement fluid in the perioperative and critical care setting. Its potential advantages as a highly effective volume expander must be weighed, however, against its potential harm for patients in the context of various neurological states and for various neurosurgical interventions. This narrative review explores the physiological considerations of intravenous human albumin as a replacement fluid and examines the extant clinical evidence for and against its use within the various facets of modern neuroanesthesia and neurocritical care practice.