Phenotype of BTK‐lacking myeloid cells during prolonged COVID‐19 and upon convalescent plasma. (19th October 2022)

• Record Type: Journal Article
• Authors: Gomes, André M. C.; Farias, Guilherme B.; Trombetta, Amelia C.; Godinho‐Santos, Ana; Parreira, Inês; Gonçalves, Hélder Diogo; Simões, Mariana Lessa; Aguiar, Patrício; Deveza, Maria Manuel; Inácio, João; Sousa, Ana E.; da Silva, Susana Lopes
• Is Part Of: European journal of haematology. Volume 110:Number 2(2023)
• Page Start: 209
• Page End: 212
• Publication Date: 2022-10-19
• Subjects: BTK -- COVID‐19 -- innate immunity -- monocytes -- SARS‐CoV‐2 -- X‐linked agammaglobulinemia; Hematology -- Periodicals; Blood -- Diseases -- Periodicals; Blood -- Periodicals; 616.15005
• DOI: 10.1111/ejh.13881
• Languages: English
• ISSNs: 0902-4441

Abstract

Abstract: XLA patient with 7‐month course of COVID‐19 with persistent plasma SARS‐CoV‐2 load revealed a sustained non‐inflammatory profile of myeloid cells in association with contained severity of disease, arguing in favor of the use of BTK inhibitors in SARS‐COV‐2 infection.