High precision magnetoencephalography reveals increased right-inferior frontal gyrus beta power during response conflict. (January 2023)

• Record Type: Journal Article
• Authors: Daniel, Pria L.; Bonaiuto, James J.; Bestmann, Sven; Aron, Adam R.; Little, Simon
• Is Part Of: Cortex. Volume 158(2023)
• Page Start: 127
• Page End: 136
• Publication Date: 2023-01
• Subjects: R-IFG beta -- Response conflict -- Switching -- hpMEG -- pre-SMA theta; Neuropsychology -- Periodicals; Nervous system -- Periodicals; Neurology -- Periodicals; Psychophysiology -- Periodicals; Behavior -- Periodicals; Neurology -- Periodicals; 612.825
• DOI: 10.1016/j.cortex.2022.10.007
• Languages: English
• ISSNs: 0010-9452

Abstract

Abstract: Flexibility of behavior and the ability to rapidly switch actions is critical for adaptive living in humans. It is well established that the right-inferior frontal gyrus (R-IFG) is recruited during outright action-stopping, relating to increased beta (12–30 Hz) power. It has also been posited that inhibiting incorrect response tendencies and switching is central to motor flexibility. However, it is not known if the commonly reported R-IFG beta signature of response inhibition in action-stopping is also recruited during response conflict, which would suggest overlapping networks for stopping and switching. In the current study, we analyzed high precision magnetoencephalography (hpMEG) data recorded with multiple within subject recording sessions (trials n > 10, 000) from 8 subjects during different levels of response conflict. We hypothesized that a R-IFG-triggered network for response inhibition is domain general and therefore also involved in mediating response conflict. We tested whether R-IFG showed increased beta power dependent on the level of response conflict. Using event-related spectral perturbations and linear mixed modeling, we found that R-IFG beta power increased for response conflict trials. The R-IFG beta increase was specific to trials with strong response conflict, and increased R-IFG beta power related to less error. This supports a more generalized role for R-IFG beta, beyond simple stopping behavior towards response switching.