Trends and outcomes of cardiogenic shock in Asian populations compared with non-Asian populations in the US: NIS Analysis (2002-2019). (2nd January 2023)

• Record Type: Journal Article
• Authors: Sandhyavenu, Harigopal; Ullah, Waqas; Badu, Irisha; Taha, Amro; Polam, Aravind Reddy; Mir, Tanveer; Brailovsky, Yevgeniy; Rajapreyar, Indranee N.; Vallabhajosyula, Saraschandra; Alraies, M Chadi
• Is Part Of: Expert review of cardiovascular therapy. Volume 21:Number 1(2023)
• Page Start: 67
• Page End: 74
• Publication Date: 2023-01-02
• Subjects: Cardiogenic shock -- Asian population -- coronary artery bypass graft -- mechanical circulatory support; Cardiovascular agents -- Research -- Periodicals; 616.12061
• DOI: 10.1080/14779072.2023.2162040
• Languages: English
• ISSNs: 1477-9072

Abstract

ABSTRACT: Background: Current understanding of outcomes of cardiogenic shock (CS) in Asian populations is limited. We aim to study the clinical outcomes of CS in Asian population compared with non-Asians in the US. Methods: The National Inpatient Sample (NIS) database was queried between 2002-2019 to identify hospitalizations with CS. Race was classified as Asians and non-Asians. The adjusted odds ratios (aOR) for in-hospital outcomes were calculated using multivariate logistic regression analysis. Results: Results Of 1, 573, 285 CS hospitalizations, 48, 398 (3%) were Asians and 1, 524, 887 (97%) were non-Asians between 2002-2019. Adjusted odds of in-hospital mortality (aOR 1.03, 95% CI 1.01–1.05), and use of intra-aortic balloon pump (IABP) (aOR 1.15, 95% CI 1.12–1.17) were significantly higher among Asians compared with non-Asians. The in-hospital mean cost of hospitalization was higher in Asian population ($63, 787±$80, 261) with CS compared with non-Asians ($56, 207±$76, 120, p < 0.001). The use of Impella (aOR 0.90, 95% CI 0.86–0.95) and left ventricular assist devices (LVAD) (aOR 0.71, 95% CI 0.65–0.77) were lower with no difference in the use of extracorporeal membrane oxygenation (ECMO) compared with non-Asians. Conclusion: Asian populations with CS have higher in-hospital mortality, increased requirement of IABP and higher mean cost of hospitalization compared with non-Asians.