930 FULL EVALUATION OF LEFT AND RIGHT ATRIAL FUNCTION AFTER TAVI IMPLANTATION. (15th December 2022)

• Record Type: Journal Article
• Authors: Giamundo, Angelo; Aquila, Iolanda; Sorrentino, Sabato; Bellantoni, Antonio; Panarello, Alessandra; Bruno, Federica; Spinali, Martina; Sportelli, Martina; Mascaro, Giuseppina; Mongiardo, Annalisa; Indolfi, Ciro; Spaccarotella, Carmen
• Is Part Of: European heart journal supplements. Volume 24(2022)Supplement K
• Publication Date: 2022-12-15
• Subjects: Cardiology -- Periodicals; Cardiology -- Europe -- Periodicals; 616.12005
• DOI: 10.1093/eurheartjsupp/suac121.193
• Languages: English
• ISSNs: 1520-765X

Abstract

Abstract: Aims: patients with severe aortic stenosis (AS) experience an increase in left ventricular filling pressure. This leads to changes in the structure and a deterioration in the function of the left (LA) and right (RA) atrium. Patients undergoing TAVI usually experience a reduction in the filling pressure of the left ventricle, thereby decreasing the wall tension of the atria in a retrograde way. The aim of this study was to demonstrate that patients with severe AS, undergoing TAVI, experience a positive remodeling of left and right atrium, with an improvement of their function. Methods and results: we enrolled 38 symptomatic patients with severe AS (mean age 84, 75 ± 12 years, 60% male, and pre-TAVI aortic valve area 0.75 ± 0.25 cm 2 and mean gradient 47, 96 ± 23 mmHg). 2D transthoracic echocardiography and 2D speckle tracking echocardiography at baseline and 12 months of follow up were performed. The variation of continuous variables was evaluated using a Student's T test for paired data. P values < 0.05 were considered significant. When compared to baseline, at 12 months a statistically significant improvement was observed for RA strain (p < 0.001) and LA (biplane) strain reservoir, conduction and contraction (p < 0.001, p < 0.012 and p < 0.001, respectively). The LA FE increased significantly (26.01 ± 9.16 vs 32.66 ± 10.95; p < 0.001). After TAVI, the LA (biplane) strain reservoir/end systolic volume ratio increased by 0.33 ± 0.18 to 0.49 ± 0.26 (p > 0.001). Left atrial end-systolic and end-diastolic volume decreased significantly (p > 0.001). Conclusion: within 12 months after TAVI, there was a reverse LA and RA remodeling and an improvement in strain reservoir, condunction and contraction function. Also, there was a significant improvement of LA (biplane) strain reservoir/end systolic volume ratio.