Decarboxylative ring-opening of 2-oxazolidinones: a facile and modular synthesis of β-chalcogen amines. Issue 53 (30th November 2022)

• Record Type: Journal Article
• Authors: Galetto, Fábio Z.; da Silva, Cleiton; Beche, Ricardo I. M.; Balaguez, Renata A.; Franco, Marcelo S.; de Assis, Francisco F.; Frizon, Tiago E. A.; Su, Xiao
• Is Part Of: RSC advances. Volume 12:Issue 53(2022)
• Page Start: 34496
• Page End: 34502
• Publication Date: 2022-11-30
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d2ra06070a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : This study includes a new protocol for the synthesis of primary and secondary β-chalcogen amines (Se, Te and S) from the ring-opening reaction of non-activated 2-oxazolidinones with chalcogenolate anions. Abstract : We report herein the synthesis of primary and secondary β-chalcogen amines through the regioselective ring-opening reaction of non-activated 2-oxazolidinones promoted by in situ generated chalcogenolate anions. The developed one-step protocol enabled the preparation of β-selenoamines, β-telluroamines and β-thioamines with appreciable structural diversity and in yields of up to 95%.