A case report of recurrent Well's syndrome masquerading as cellulitis. Issue 6 (2nd November 2021)

• Record Type: Journal Article
• Authors: Qureshi, Anum; Manley, Jasmine; Flack, Tristan; Lowitt, Mark H.
• Is Part Of: Journal of community hospital internal medicine perspectives. Volume 11:Issue 6(2021)
• Page Start: 866
• Page End: 870
• Publication Date: 2021-11-02
• Subjects: Well's syndrome -- prednisone -- cellulitis; Internal medicine -- Periodicals; Hospitals -- Periodicals; Hospitals, Community; Internal Medicine; Hospitals; Internal medicine; Periodicals; Periodicals; 610
• DOI: 10.1080/20009666.2021.1979737
• Languages: English
• ISSNs: 2000-9666

Abstract

ABSTRACT: Eosinophilic cellulitis (Well's syndrome) is a rare relapsing inflammatory disorder characterized by infiltration of eosinophils into the dermis. Although rare, WS should be considered in patients with a history of asthma and skin lesions that are resistant to antibiotic therapy. We report a case of recurrent WS. A 67-year-old woman with a history of asthma presented with a longstanding left pretibial ulcer with surrounding erythema, pain, and serous drainage, which had failed treatment with oral and parenteral antibiotics. Skin biopsy revealed eosinophilic cellulitis. Rapid improvement occurred with systemic steroid treatment; however, recurrent disease in the perineum developed as corticosteroids were tapered.