Non-hazardous Baeyer–Villiger oxidation of levulinic acid derivatives: alternative renewable access to 3-hydroxypropionates. Issue 14 (13th January 2015)

• Record Type: Journal Article
• Authors: Fink, Michael J.; Mihovilovic, Marko D.
• Is Part Of: Chemical communications. Volume 51:Issue 14(2015)
• Page Start: 2874
• Page End: 2877
• Publication Date: 2015-01-13
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc08734h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Baeyer–Villiger monooxygenases catalyze the energetically challenging oxidation of levulinates (4-oxopentanoates) to 3-hydroxypropionic acid (3-HPA) derivates under ambient conditions, replacing propellant-grade H2 O2 with aerial oxygen as the oxidant. Abstract : Baeyer–Villiger monooxygenases catalyze the energetically challenging oxidation of levulinates (4-oxopentanoates) to 3-hydroxypropionic acid (3-HPA) derivates under ambient conditions, replacing propellant-grade H2 O2 with aerial oxygen as the oxidant. This reaction enables a new pathway to a platform for chemical 3-HPA, an important intermediate in the non-petrol based production of a variety of bulk chemicals (acrylates, malonates, 1, 3-propanediol).