A novel machine learning algorithm has the potential to reduce by 1/3 the quantity of ILR episodes needing review. (14th October 2021)

• Record Type: Journal Article
• Authors: Rosier, A; Crespin, E; Lazarus, A; Laurent, G; Menet, A; Gozlan, A; Varma, N
• Is Part Of: European heart journal. Volume 42(2021)Supplement 1
• Publication Date: 2021-10-14
• Subjects: Implantable Loop Recorder; Cardiology -- Periodicals; Heart -- Diseases -- Periodicals; 616.12005
• DOI: 10.1093/eurheartj/ehab724.0316
• Languages: English
• ISSNs: 0195-668X

Abstract

Abstract: Background: Implantable Loop Recorders (ILRs) are increasingly used and generate a high workload for timely adjudication of ECG recordings. In particular, the excessive false positive rate leads to a significant review burden. Purpose: A novel machine learning algorithm was developed to reclassify ILR episodes in order to decrease by 80% the False Positive rate while maintaining 99% sensitivity. This study aims to evaluate the impact of this algorithm to reduce the number of abnormal episodes reported in Medtronic ILRs. Methods: Among 20 European centers, all Medtronic ILR patients were enrolled during the 2nd semester of 2020. Using a remote monitoring platform, every ILR transmitted episode was collected and anonymised. For every ILR detected episode with a transmitted ECG, the new algorithm reclassified it applying the same labels as the ILR (asystole, brady, AT/AF, VT, artifact, normal). We measured the number of episodes identified as false positive and reclassified as normal by the algorithm, and their proportion among all episodes. Results: In 370 patients, ILRs recorded 3755 episodes including 305 patient-triggered and 629 with no ECG transmitted. 2821 episodes were analyzed by the novel algorithm, which reclassified 1227 episodes as normal rhythm. These reclassified episodes accounted for 43% of analyzed episodes and 32.6% of all episodes recorded. Conclusion: A novel machine learning algorithm significantly reduces the quantity of episodes flagged as abnormal and typically reviewed by healthcare professionals. Funding Acknowledgement: Type of funding sources: None.