A Dense Conformal Electrode Array for High Spatial Resolution Stimulation of Electrosensory Systems. Issue 1 (5th August 2022)

• Record Type: Journal Article
• Authors: Kumar, Vikrant; Yu, Caroline; McGinn, Christine K.; Perks, Krista E.; Thompson, Sarah M.; Sawtell, Nathaniel B.; Kymissis, Ioannis
• Is Part Of: Advanced materials technologies. Volume 8:Issue 1(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-08-05
• Subjects: electric fish -- electrode array -- flexible -- neurophysiology -- stimulation; Materials science -- Periodicals; Technological innovations -- Periodicals; Materials science; Technological innovations; Periodicals; 620.1105
• DOI: 10.1002/admt.202200354
• Languages: English
• ISSNs: 2365-709X

Abstract

Abstract: Studies of electrosensory systems have led to insights into a number of general issues in biology. However, investigations of these systems have been limited by the inability to precisely control spatial patterns of electrosensory input. In this paper, an electrode array and a system to selectively stimulate spatially restricted regions of an electroreceptor array are presented. The array has 96 channels consisting of chrome/gold electrodes patterned on a flexible parylene‐C substrate and encapsulated with another parylene‐C layer. The conformability of the electrode array allows for optimal current driving and surface interface conditions. Recordings of neural activity at the first central processing stage in weakly electric mormyrid fish support the potential of this system for high spatial resolution stimulation and mapping of electrosensory systems. Abstract : This work presents a flexible, conformal, and dense electrode array and electronic system capable of stimulation of electrosensory systems through activation of different individual terminal sites on an electrode array. In vivo neural recordings at the first central processing stage show its capability to drive graded and spatially specific neuronal responses in a weakly electric mormyrid fish.