Cyclopentenone and wickerol derivatives from the marine algicolous fungus Trichoderma atroviride A-YMD-9-4. Issue 2 (17th January 2023)

• Record Type: Journal Article
• Authors: Yin, Xiu-Li; Song, Yin-Ping; Liu, Xiang-Hong; Ji, Nai-Yun
• Is Part Of: Natural product research. Volume 37:Issue 2(2023)
• Page Start: 277
• Page End: 282
• Publication Date: 2023-01-17
• Subjects: Trichoderma -- cyclopentenone -- hypocrenone -- wickerol; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2021.1969568
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new cyclopentenone derivative, 4-hydroxyhypocrenone A, and a new naturally-occurring wickerol derivative, 8-acetoxywickerol A, as well as two known compounds, hypocrenone A and wickerol B, were purified from Trichoderma atroviride A-YMD-9-4, an endophytic fungus isolated from the marine red alga Gracilaria verrucosa . The structures and relative configurations of two new isolates were established by a combination of 1 D/2D NMR, IR, and mass spectroscopic methods, and the absolute configuration of 1 was assigned on the basis of ECD data analyzed by quantum chemical calculations. Compounds 1 and 2 exhibited weak inhibition of one or two marine phytoplankton species. Graphical Abstract: UF0001