Development of novel mechanisms for housing, handling, and remote monitoring of common marmosets at animal biosafety level 3. Issue 2 (1st July 2014)

• Record Type: Journal Article
• Authors: Powell, Diana S.; Walker, Reagan C.; Heflin, Dennis T.; Fisher, Dan; Kosky, Joseph B.; Homer, Lesley C.; Reed, Douglas S.; Stefano Cole, Kelly; Trichel, Anita M.; Hartman, Amy L.
• Is Part Of: Pathogens and disease. Volume 71:Issue 2(2014:Jul.)
• Page Start: 219
• Page End: 226
• Publication Date: 2014-07-01
• Subjects: biosafety level 3 -- Regional Biocontainment Laboratory -- Rift Valley fever virus -- radiotelemetry; Medical microbiology -- Periodicals; Pathogenic microorganisms -- Periodicals; Communicable diseases -- Microbiology -- Periodicals; Communicable diseases -- Pathogenesis -- Periodicals; Host-parasite relationships -- Periodicals; Systems biology -- Periodicals; 616.904105
• DOI: 10.1111/2049-632X.12140
• Languages: English
• ISSNs: 2049-632X

Abstract

Abstract: The use of common marmosets as an alternative non human primate model for infectious disease research using BSL 3 viruses such as Rift Valley fever virus (RVFV) presents unique challenges with respect to housing, handling, and safety. Subject matter experts from veterinary care, animal husbandry, biosafety, engineering, and research were consulted to design a pilot experiment using marmosets infected with RVFV. This paper reviews the caging, handling, and safety related adaptations and modifications that were required to humanely utilize marmosets as a model for high hazard BSL 3 viral diseases. Abstract : The authors review the caging, handling, and safety related adaptations and modifications that were required to humanely utilize marmosets as a model for high hazard BSL 3 viral diseases. Abstract :