MareyMap Online: A User-Friendly Web Application and Database Service for Estimating Recombination Rates Using Physical and Genetic Maps. (6th September 2017)

• Record Type: Journal Article
• Authors: Siberchicot, Aurélie; Bessy, Adrien; Guéguen, Laurent; Marais, Gabriel AB
• Is Part Of: Genome biology and evolution. Volume 9:Number 10(2017:Oct.)
• Page Start: 2506
• Page End: 2509
• Publication Date: 2017-09-06
• Subjects: crossover rates -- Marey map approach -- R package -- Shiny -- web applications; Genomics -- Periodicals; Genes -- Periodicals; 572.8605
• DOI: 10.1093/gbe/evx178
• Languages: English
• ISSNs: 1759-6653

Abstract

Abstract: Given the importance of meiotic recombination in biology, there is a need to develop robust methods to estimate meiotic recombination rates. A popular approach, called the Marey map approach, relies on comparing genetic and physical maps of a chromosome to estimate local recombination rates. In the past, we have implemented this approach in an R package called MareyMap, which includes many functionalities useful to get reliable recombination rate estimates in a semi-automated way. MareyMap has been used repeatedly in studies looking at the effect of recombination on genome evolution. Here, we propose a simpler user-friendly web service version of MareyMap, called MareyMap Online, which allows a user to get recombination rates from her/his own data or from a publicly available database that we offer in a few clicks. When the analysis is done, the user is asked whether her/his curated data can be placed in the database and shared with other users, which we hope will make meta-analysis on recombination rates including many species easy in the future.