Faster Initial Viral Decay in Female Children Living With HIV. (25th January 2021)

• Record Type: Journal Article
• Authors: Domínguez-Rodríguez, Sara; Serna-Pascual, Miquel; Foster, Caroline; Palma, Paolo; Nastouli, Eleni; De Rossi, Anita; Seoane, Javier; Rossi, Paolo; Giaquinto, Carlo; Tagarro, Alfredo; Rojo, Pablo
• Is Part Of: Journal of the Pediatric Infectious Diseases Society. Volume 10:Number 5(2021)
• Page Start: 674
• Page End: 676
• Publication Date: 2021-01-25
• Subjects: HIV-1 -- pediatrics -- reservoir -- sex -- viral decay; Communicable diseases in children -- Periodicals; Children -- Diseases -- Periodicals; 618.929
• DOI: 10.1093/jpids/piaa174
• Languages: English
• ISSNs: 2048-7193

Abstract

Abstract: Limited data exist regarding sex bias and viral decay in children with HIV. We investigated the sex differences in viral decay in 25 perinatally HIV-infected children. Females presented faster phase I viral decay regardless of their age at antiretroviral therapy (ART) initiation, baseline CD4 percentages, or baseline RNA levels. Also, for each month elapsed under ART, females had faster viral decay than males. Abstract : We investigated the sex differences in viral decay in 25 HIV perinatally infected children. Females presented faster phase-I viral decay regardless their age at ART initiation, baseline CD4 percentage, or baseline RNA levels.