EP026/#1090 Breast cancer in young women. (4th December 2022)

• Record Type: Journal Article
• Authors: Chermiti, Amal; Bettaieb, Hajer; Bouhmida, Rahma; Souayeh, Nesrine; Lamiri, Hadir; Ouederni, Meriem; Rouiss, Hadhami; Abidi, Idriss; Oueslati, Hedhili; Mbarki, Chaouki
• Is Part Of: International journal of gynecological cancer. Volume 32(2022)Supplement 3
• Page Start: A59
• Page End: A60
• Publication Date: 2022-12-04
• Subjects: Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2022-igcs.117
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Objectives: We aimed in our study to analyse clinical and epidemiological as well as histopathological properties and management plus the outcome of breast cancer in young women. Methods we conducted a descriptive retrospective study including 38 young women (=<40 years old) operated for breast cancer in the obstetrics and gynaecology department of Ben Arous hospital between January 2012 and December 2019. Data were collected from hospital records involving: *epidemiological, clinical and histopathological properties. *Received treatment. *Outcome after treatment. Results: Among 150 patients operated for breast cancer 26% were younger than 40 years old. The middle age was 37+-2 years . Ten percent of these patients had a medical history of breast cancer in their family. Twenty percent of them were nulliparous and 69% had breastfed their babies. Pregnancy was noticed in 15% of cases and 15% used oestrogen-progestin combination as a contraceptive method. Fifty six percent of patients were diagnosed with stage 2 disease and 20% with stage 4. Pathological subtype was invasive ductal carcinoma in 92% of cases and 80% were triple negative. Treatment strategy was mainly based on a radical surgery with radiotherapy and chemotherapy. During the follow up period, metastatic disease occurred in 15% of cases. Five patients died due to disease progression. Overall survival after treatment was about 86%. Conclusions: Young breast cancer patients seem to have a more aggressive disease course. That's why the management of this special patient population requires an interdisciplinary approach.