Application of a Discrete Choice Experiment to Assess Adherence-Related Motivation Among Adolescents and Young Adults With Cancer. (25th July 2017)

• Record Type: Journal Article
• Authors: McGrady, Meghan E; Prosser, Lisa A; Thompson, Aimee N; Pai, Ahna L H
• Is Part Of: Journal of pediatric psychology. Volume 43:Number 2(2018)
• Page Start: 172
• Page End: 184
• Publication Date: 2017-07-25
• Subjects: adherence -- adolescent -- cancer -- discrete choice experiment -- young adult; Clinical child psychology -- Periodicals; 618.9289005
• DOI: 10.1093/jpepsy/jsx104
• Languages: English
• ISSNs: 0146-8693

Abstract

Abstract: Objective: To develop and pilot test a discrete choice experiment (DCE) to assess the specific factors likely to motivate a given adolescent or young adult with cancer to adhere to medications included in treatment protocols. Methods: A multimethod and iterative approach was used. Twenty adolescents and young adults with cancer participated in DCE pilot testing and refinement. Hierarchical Bayes was used to estimate attribute and attribute-level preference scores for each participant. Results: The final DCE included nine choice sets composed of four attributes. The resulting DCE was modified with feedback from 20 adolescents and young adults ( M [ SD ] age = 18.66 [2.95]) with cancer. The DCE was understandable and relevant. The factors likely to motivate adolescents and young adults with cancer to be adherent differed across individuals. Conclusions: DCEs including the measure developed in this manuscript offer a novel approach to understanding individual-level differences critical for informing adherence-promotion efforts.