Graphene oxide nanomaterials in the recovery of shoulder joint movement contraction. (4th February 2023)

• Record Type: Journal Article
• Authors: Zhu, Yayun
• Is Part Of: International journal of nanotechnology. Volume 19:Number 6/11(2022)
• Page Start: 720
• Page End: 735
• Publication Date: 2023-02-04
• Subjects: graphene oxide -- titanium dioxide nanotube -- antibacterial ability -- mesenchymal stem cells -- shoulder joint -- recovery; 620.505
• Languages: English
• ISSNs: 1475-7435

Abstract

The drug loading capacity, the drug releasing capacity, and the antibacterial ability of the GO-TiO2 nanotubes were analysed. The results showed that after seven days of culture, the cell adhesion rate on GO-TiO2 surface (79.9%) was obviously higher than that on pure titanium surface (52%) (P < 0.05); the mesenchymal stem cells (MSCs) on GO-TiO2 nanotubes surface were in the form of polymerised colonies, while the MSCs on the surface of pure Ti were in the form of dispersed particles. The drug-loaded GO-TiO2 nanotube film did not release the drug after eight days, while the drug release time of the drug-loaded GO-TiO2 nanotube film covered by poly(lactide-coglycolide) (PLGA) was extended to 24 days. The antibacterial ability of pure Ti, GO-TiO2 nanotubes, and drug-loaded GO-TiO2 nanotubes was compared as pure Ti < GO-TiO2 nanotubes<drug-loaded GO-TiO2 nanotubes. Therefore, it was very useful for monitoring the recovery of exercise contraction function.