Understanding cyclic(alkyl)(amino)carbene–copper complex catalysed N–H and O–H bond addition to electron deficient olefins. Issue 3 (7th December 2022)

• Record Type: Journal Article
• Authors: Tyagi, Akshi; Mondal, Sunita; Anmol, ; Tiwari, Vikas; Karmakar, Tarak; Kundu, Subrata
• Is Part Of: Chemical communications. Volume 59:Issue 3(2023)
• Page Start: 110
• Page End: 113
• Publication Date: 2022-12-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc05613e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The cyclic(alkyl)(amino)carbene–copper complex (CAAC–CuCl) showed an excellent performance towards the hydroamination and hydroalkoxylation reactions of electron deficient olefins. Theoretical investigations revealed the mechanism of these reactions. Abstract : The hydroamination of electron-deficient olefins was carried out using the (CAAC)Cu–Cl (CAAC = cyclic (alkyl)(amino)carbene) catalyst with an excellent yield at room temperature and under an open atmosphere. Furthermore, the catalyst shows excellent efficiency in the hydroaryloxylation and hydroalkoxylation of alkenes under mild conditions. The efficiency of the catalyst was tested for a wide range of substrates with different electronic and steric functionalities. Detailed computational studies have been carried out to understand the mechanism of these Cu(i ) catalyzed reactions, which revealed that the reaction proceeds via either a four-membered or a six-membered cyclic transition state containing the copper ion.