Selectfluor®-enabled photochemical selective C(sp3)–H(sulfonyl)amidation. Issue 3 (7th December 2022)

• Record Type: Journal Article
• Authors: Chen, Yuehua; Yang, Boxuan; Li, Qian-Yu; Lin, Yu-Mei; Gong, Lei
• Is Part Of: Chemical communications. Volume 59:Issue 3(2023)
• Page Start: 118
• Page End: 121
• Publication Date: 2022-12-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc05569d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Chemo- and site-selective C(sp 3 )–H sulfonylamidation and amidation of toluene derivatives, cycloalkanes, natural products and bioactive molecules has been achieved by employing Selectfluor® as a versatile reagent. Abstract : Transition metal- and photosensitizer-free C(sp 3 )–H (sulfonyl)amidation reactions have been realized by employing Selectfluor® as a versatile reagent, functioning as a photoactive component, a HAT precursor and an oxidant. Various toluene derivatives, cycloalkanes, natural products and bioactive molecules can be converted into N -containing products under mild conditions in good yield and with high chemo- and site-selectivity.